High-Protein Ground Beef Casserole

Posted on December 25, 2025

by: Amelia Grace

High-protein ground beef casserole served in a baking dish

There’s nothing quite like a dish that brings a family together, and this ground beef casserole is a champion at doing just that. Packed with protein around 20 grams per serving, it delivers a hearty, comforting meal that encapsulates everything home-cooked and delicious. Imagine the wafting aroma of seasoned beef mingling with melted cheese, creating a scene that beckons everyone to the table. Whether it’s a chilly evening or a busy weekday, this casserole will feel right at home on your dining table.

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Ground Beef Casserole


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  • Author: james-carter
  • Total Time: 45 minutes
  • Yield: 4 servings 1x
  • Diet: None

Description

A hearty and comforting ground beef casserole that brings families together with its delicious flavors and protein-packed goodness.


Ingredients

Scale
  • 1 pound lean ground beef
  • 1 cup diced onion
  • 1/2 cup diced orange bell pepper
  • 1/4 teaspoon red pepper flakes
  • 1 teaspoon Montreal Steak seasoning or Magic Dust seasoning
  • 16 ounces tomato sauce
  • 10 ounces can of Red Gold Diced Tomatoes & Green Chiles
  • 1 1/2 teaspoon dried oregano
  • 2 teaspoon chili powder
  • 2 cups frozen corn
  • 2 ounces shredded Mexican 4 Cheese blend
  • 1 1/2 cups dried macaroni style pasta cooked al dente
  • 1 cup shredded Mexican 4 Cheese blend
  • Sliced green onions for garnish

Instructions

  1. Preheat the oven to 325 degrees F.
  2. Spray a two-quart casserole dish with cooking spray.
  3. In a large skillet, brown the ground beef with onions, bell pepper, and red pepper flakes for about 5-7 minutes.
  4. Season the mixture with Montreal Steak seasoning or Magic Dust seasoning.
  5. Add the tomato sauce, diced tomatoes, oregano, and chili powder; stir well and bring to a gentle boil.
  6. Reduce heat and let simmer for 15-20 minutes.
  7. Stir in the frozen corn and simmer for a few more minutes.
  8. Remove from heat and stir in 2 ounces of cheese until melted.
  9. Gently stir in the cooked pasta until well mixed.
  10. Pour the mixture into the prepared casserole dish and top with the remaining shredded cheese.
  11. Bake uncovered for 20-30 minutes or until the top is golden brown and bubbling.
  12. Garnish with sliced green onions and serve.

Notes

For a creamier texture, mix in a dollop of sour cream before baking. You can also add black beans for extra protein and flavor!

  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 1 serving
  • Calories: 350
  • Sugar: 5g
  • Sodium: 600mg
  • Fat: 15g
  • Saturated Fat: 6g
  • Unsaturated Fat: 7g
  • Trans Fat: 0g
  • Carbohydrates: 40g
  • Fiber: 4g
  • Protein: 20g
  • Cholesterol: 70mg

Why This Ground Beef Casserole is an All-Time Favorite

Let’s get real—life is busy, and when it comes to dinner, we all crave something simple yet satisfying. This ground beef casserole doesn’t just fit the bill; it scores a home run on flavor and ease. After just one bake, you’ll see why families keep returning to this recipe, day after day. It’s a medley of vibrant colors and mouthwatering tastes, promising the perfect recipe to bond over, whether you’re catching up over plates or reminiscing about the day’s adventures.

What You’ll Need

To whip up this crowd-pleaser, you’ll need to gather the following ingredients, each crucial to making this dinner both hearty and flavorful:

  • 1 pound lean ground beef
  • 1 cup diced onion
  • 1/2 cup diced orange bell pepper
  • 1/4 teaspoon red pepper flakes
  • 1 teaspoon Montreal Steak seasoning or Magic Dust seasoning
  • 16 ounces tomato sauce
  • 10 ounces can of Red Gold Diced Tomatoes & Green Chiles
  • 1 1/2 teaspoon dried oregano
  • 2 teaspoon chili powder
  • 2 cups frozen corn
  • 2 ounces shredded Mexican 4 Cheese blend
  • 1 1/2 cups dried macaroni style pasta cooked al dente
  • 1 cup shredded Mexican 4 Cheese blend
  • Sliced green onions for garnish

The Smart Sequence

Cooking doesn’t need to be complicated. Follow these straightforward steps and watch your ground beef casserole come to life:

  1. Preheat the oven to 325 degrees.
  2. Spray a two-quart casserole dish with cooking spray.
  3. In a large skillet, brown the ground beef with onions, bell pepper, and red pepper flakes, around 5-7 minutes—this brings out those savory flavors!
  4. Season the mixture with the Magic Dust or Montreal Steak seasoning, ensuring every bite is delicious.
  5. Add the tomato sauce, diced tomatoes, oregano, and chili powder, stirring well before bringing to a gentle boil.
  6. Reduce the heat and let it simmer for 15-20 minutes to allow the flavors to meld together.
  7. Stir in the frozen corn and let it simmer for a few more minutes—this adds sweetness to the dish.
  8. Remove from heat and stir in the 2 ounces of cheese until melted.
  9. Gently stir in the cooked pasta, making sure everything is well mixed and coated in that cheesy goodness.
  10. Pour all ingredients into the prepared casserole dish and top with the remaining shredded cheese.
  11. Bake uncovered for 20-30 minutes or until the top is golden brown and bubbling.
  12. Garnish with sliced green onions if desired for that extra pop of flavor and color.

Nutrition Breakdown

Each serving of this comforting dish is approximately 350 calories, with 20 grams of protein, 40 grams of carbohydrates, 15 grams of fat, and 4 grams of fiber. The balance of protein and fiber makes this casserole a good choice for fueling energy and satisfaction at the dinner table. Paired with a side salad, it becomes a nourishing meal that everybody can help themselves to with pleasure.

Perfect Pairings

Serving this ground beef casserole is a breeze. It pairs beautifully with a crisp side salad, laden with fresh greens, cherry tomatoes, and a tangy vinaigrette. For those chilly nights, some crusty bread makes a perfect companion for sopping up the saucy goodness. Come summer, add a side of grilled vegetables to embrace those warm evenings.

How to Store It Right

Once everyone has had their fill, you can store any leftovers in an airtight container in the fridge for up to 3 days. For longer storage, consider freezing portions for up to 3 months—just be sure to label your containers! When reheating, the best method is to use the oven, which will restore that crispy top and melty cheese, or simply microwave individual servings for convenience.

Expert Tips

  1. Opt for lean ground beef—it keeps the dish lighter but still packed with flavor.
  2. Consider adding black beans for extra protein and fiber, sneaking in even more nutritious ingredients!
  3. For a creamier texture, mix in a dollop of sour cream before baking.
  4. Broil for the last 2-3 minutes of baking for an extra crispy top.
  5. Incorporate seasonal veggies, like zucchini or spinach, to switch things up depending on what’s fresh and available.

Flavor Experiments

Feeling adventurous? Here are some great ways to switch up the flavors:

  • Add a seasonal twist by incorporating roasted butternut squash in the fall for a sweeter undertone.
  • For a gourmet touch, sprinkle crumbled feta cheese atop just before serving for a burst of tangy richness.
  • Have fun and mix in Tex-Mex flavors by adding some taco seasoning or jalapeños for a bit of spice!

Learn from My Mistakes

Even seasoned chefs have their off days, so here are a few pitfalls to avoid:

  1. Skipping the simmering step—don’t rush this! It’s essential for flavor development.
  2. Using low-fat cheese can lead to a rubbery texture. Always stick to regular cheese for that perfect melt.
  3. Overcooking the pasta before adding it to the casserole—keep it al dente, as it will continue to cook in the oven.
  4. Forgetting to preheat your oven can result in longer cooking times and uneven baking.
  5. Under-seasoning—always taste as you go! Don’t be shy to add extra spices to match your palate.

What to Do with Leftovers

Don’t let those leftovers go to waste!

  • Transform it into a hearty wrap by scooping leftovers onto a tortilla with some fresh greens and a drizzle of ranch dressing.
  • Make a delicious beef casserole soup by adding broth and garnishing with fresh herbs for a new take the next day.
  • Or, mix in some eggs, pour into a baking dish, and bake for a savory breakfast casserole—yes, please!

Quick Questions

Can I make this casserole ahead of time? Absolutely! You can assemble it in advance and bake it just before serving. It’s perfect for those nights you know you’ll be rushed.

What can I substitute for ground beef? Ground turkey or chicken works well if you’re looking for a leaner option, while crumbled tofu is great for a vegetarian twist.

Can I add other vegetables? Yes, feel free to mix in anything you like! Bell peppers, spinach, and even carrots can add both flavor and nutrition.

How can I make this dish spicier? Easy! Just add extra red pepper flakes or toss in some diced jalapeños to your beef mixture for a flavor punch.

This ground beef casserole isn’t just a recipe; it’s a meal infused with love and nostalgia, a dish that reminds us of home and family gatherings. Now that you have the magic formula, get ready to create your own wonderful memories around the dinner table!

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