High-Protein- Ground Beef Zucchini Casserole

Posted on January 18, 2026

by: James Carter

Delicious Beef Zucchini Casserole served in a baking dish

When it comes to family dinners, there’s a timeless struggle: how to please both picky eaters and gourmet palettes. Whipping up a dish that balances flavor, nutrition, and satisfaction can sometimes feel like a high-wire act. But let’s talk about Ground Beef Zucchini Casserole, an ingenious blend of comfort food that packs a punch of nutrients. Not only does it serve up a hearty dose of protein and fiber, but the cheese, zucchini, and spices create the perfect kitchen symphony with aromas that will have everyone flocking to the table.

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beef zucchini casserole 2026 01 17 204343 1

Ground Beef Zucchini Casserole


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  • Author: james-carter
  • Total Time: 50 minutes
  • Yield: 6 servings 1x
  • Diet: None

Description

A hearty Ground Beef Zucchini Casserole combining flavors and nutrition, perfect for family dinners.


Ingredients

Scale
  • 1 cup dry quinoa, cooked
  • 2 tablespoons olive oil, divided
  • 1 lb lean ground beef
  • 3 cloves garlic, minced
  • 1 cup yellow cooking onion, diced
  • 6 zucchinis, sliced into quarter-inch rounds
  • Salt and black pepper to taste
  • 2 cups low-sugar tomato sauce
  • 1 teaspoon dried oregano
  • 1/2 teaspoon garlic powder
  • 1 tablespoon Italian seasoning
  • 1 cup cottage cheese (or ricotta cheese)
  • 2 cups mozzarella cheese, shredded
  • 2 tablespoons parmesan cheese
  • Fresh basil for topping

Instructions

  1. Preheat the oven to 375°F and grease a 9×13 inch casserole dish.
  2. Cook quinoa according to package instructions.
  3. In a large pan over medium-high heat, add 1 tablespoon of olive oil. Once hot, add ground beef, garlic, and yellow onions; cook until meat is no longer pink and onions are translucent. Drain excess oil and add meat to the casserole dish.
  4. In the same pan, add the remaining olive oil, then add the sliced zucchini with additional salt and pepper. Cover and cook for about 5 minutes until soft.
  5. To the casserole dish with the meat, add zucchini, spices, cottage cheese, cooked quinoa, sauce, and half of the mozzarella cheese. Stir together, spread evenly in the dish, and top with remaining mozzarella and Parmesan cheese.
  6. Bake for approximately 30 minutes, broiling for the last 5 minutes.
  7. Top with fresh basil and serve.

Notes

For a richer flavor, brown the ground beef with spices before adding garlic and onions.

  • Prep Time: 15 minutes
  • Cook Time: 35 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 1 cup
  • Calories: 480
  • Sugar: 7g
  • Sodium: 600mg
  • Fat: 20g
  • Saturated Fat: 10g
  • Unsaturated Fat: 8g
  • Trans Fat: 0g
  • Carbohydrates: 40g
  • Fiber: 5g
  • Protein: 35g
  • Cholesterol: 85mg

Why This Ground Beef Zucchini Casserole Stands Out

This Ground Beef Zucchini Casserole is a weeknight lifesaver that never lets you down. It brings together a rich medley of textures and flavors that the whole family will love, all in one dish—no juggling multiple pans required. If you’re seeking a foolproof recipe that turns simple ingredients into a masterpiece while saving you time, look no further. With the ease of preparation and the joy it brings to your dinner table, you’ll come to cherish this as one of your go-to meals.

What You’ll Need

  • 1 cup dry quinoa, cooked according to package instructions
  • 2 tablespoons olive oil, divided
  • 1 lb lean ground beef
  • 3 cloves garlic, minced
  • 1 cup yellow cooking onion, diced
  • 6 zucchinis (approximately 2 lbs), sliced into quarter-inch rounds
  • Salt and black pepper to taste
  • 2 cups low-sugar tomato sauce (marinara sauce)
  • 1 teaspoon dried oregano
  • 1/2 teaspoon garlic powder
  • 1 tablespoon Italian seasoning
  • 1 cup cottage cheese (or ricotta cheese)
  • 2 cups mozzarella cheese, shredded
  • 2 tablespoons parmesan cheese
  • Fresh basil for topping

Let’s Cook

  1. Preheat the oven to 375F and grease a 9×13 inch casserole dish.
  2. Cook quinoa according to package instructions.
  3. In a large pan over medium-high heat, add 1 tablespoon of olive oil. Once hot, add ground beef, garlic, and yellow onions; cook until meat is no longer pink and onions are translucent. Drain excess oil and add meat to the casserole dish.
  4. In the same pan, add the remaining olive oil, then add the sliced zucchini with additional salt and pepper. Cover and cook for about 5 minutes until soft.
  5. To the casserole dish with the meat, add zucchini, spices, cottage cheese, cooked quinoa, sauce, and half of the mozzarella cheese. Stir together, spread evenly in the dish, and top with remaining mozzarella and Parmesan cheese.
  6. Bake for approximately 30 minutes, broiling for the last 5 minutes.
  7. Top with fresh basil and serve.

Expert Tip: For a richer flavor, consider browning the ground beef with spices before adding the garlic and onions—this will help draw out the flavors early.

Balanced Bites

In a generous serving of this Ground Beef Zucchini Casserole, you’ll find approximately:

  • Serving Size: 1 cup
  • Calories: 480
  • Protein: 35g
  • Carbs: 40g
  • Fat: 20g
  • Fiber: 5g

This dish is both satisfying and packed with nutrient value! The combination of quinoa and lean beef brings healthy protein, while the zucchini adds a wonderful source of vitamins. It’s a bright dinner option that provides energy and nourishment for an active lifestyle.

Perfect Pairings

To make this dish even more delightful, consider serving it alongside a fresh garden salad adorned with crisp greens, cherry tomatoes, and a light vinaigrette. For bread lovers, a side of garlic bread can elevate the experience beautifully. The casserole is also great for those lazy Sunday afternoons, making it perfect for family gatherings or cozy nights in.

How to Store It Right

This casserole stores beautifully. Keep any leftovers in an airtight container in the fridge for up to four days. If you want to extend its life, it can be frozen for up to three months; just be sure to let it cool completely before freezing. When reheating, you can use the microwave, but for optimal texture, heat it in the oven at 350F until warmed through, about 20 minutes.

Pro Tips

  • For an added layer of flavor, sauté the zucchini with a splash of balsamic vinegar before adding it to the mix.
  • Mix in some chopped spinach or kale for extra greens; they’ll wilt down and be nearly undetectable, perfect for stealth nutrition!
  • If you prefer a crispier topping, sprinkle a bit more Parmesan on top before broiling for that golden-brown finish.

Flavor Experiments

Feeling adventurous? Here are some twists to elevate your casserole:

  • Seasonal Twist: In winter, replace zucchini with butternut squash for a naturally sweet alternative.
  • Gourmet Version: Add crumbled feta cheese into the mix for a tangy burst that pairs beautifully with the beef and tomato sauce.
  • Playful Variation: Stir in some olives or chopped sun-dried tomatoes for a Mediterranean flair that brightens up the flavor profile.

Learn from My Mistakes

  • Mistake: Skipping the draining of the ground beef can lead to a greasy casserole. Fix: Always drain after browning to keep your dish light and flavorful.
  • Mistake: Overcooking the zucchini leaves it mushy. Fix: Just a few minutes in the pan is perfect—aim for tender but still vibrant brightness.
  • Mistake: Using too much tomato sauce can make the casserole watery. Fix: Stick to the recipe and add additional sauce only if needed.

What to Do with Leftovers

  • Creative Second-Day Idea: Use the leftovers as a filling for stuffed bell peppers—just scoop out the seeds, fill with casserole, and bake until the peppers are tender.
  • Next-Day Magic: Transform it into a hearty breakfast scramble by mixing the casserole with some eggs and cooking in a skillet—say hello to a fulfilling, protein-packed brunch.

Quick Questions

Can I use ground turkey instead of beef? Absolutely! Ground turkey will work just fine, offering a leaner alternative that still packs great flavor.

How can I make this dish vegetarian? Swap the ground beef for a mix of black beans and mushrooms, giving it a hearty texture without the meat.

What’s the best way to reheat it for leftovers? Oven reheating at 350F helps retain textures, but if you’re in a hurry, microwaving in short intervals works too!

Can I prepare this dish ahead of time? Yes, you can assemble it a day in advance and store it in the fridge before baking—just give it a few extra minutes in the oven!

With its straightforward ingredients and method, this Ground Beef Zucchini Casserole is an easily adaptable and thoroughly enjoyable meal for everyone around the table. Embrace its comforting flavors, and make it a staple in your recipe rotation!

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